What is Sermorelin?
Sermorelin is a bioidentical peptide analog of growth hormone-releasing hormone (GHRH) used in anti-aging and longevity medicine. It stimulates the pituitary gland to naturally increase the production and release of human growth hormone (HGH). Unlike synthetic HGH injections, Sermorelin works upstream to support the body’s own growth hormone rhythm—making it a safer and more physiologically aligned option. It is frequently used to improve body composition, energy, recovery, sleep, skin tone, and cognitive clarity.
How does it work?
Sermorelin acts as a GHRH analog, triggering the body’s natural HGH production cascade:
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Pituitary Stimulation
• Sermorelin binds to GHRH receptors in the anterior pituitary, prompting pulsatile HGH secretion, which leads to the downstream production of IGF-1—a key driver of cellular regeneration and repair. -
Physiologic vs. Pharmacologic
• Because Sermorelin stimulates natural HGH production (rather than replacing it), the body maintains tighter control over hormone levels, reducing the risks associated with supraphysiologic dosing seen with synthetic HGH. -
Youthful Restoration
• By boosting IGF-1 and HGH, Sermorelin promotes lean muscle gain, fat loss, skin tightening, and improved sleep—restoring multiple markers of youthful function.
3 Easy steps process
Take the health questionnaire
Get your prescription
Get your meds
Why choose us?
Frequently Asked Questions
What can I expect with Sermorelin treatment?
• Administer subcutaneously at night (typically 5 nights per week) to mimic natural HGH rhythm
• Weeks 2–4: Improved sleep and mood
• Weeks 4–8: Noticeable energy, body composition, and recovery benefits
• 3–6 months: Enhanced skin tone, muscle tone, and metabolic changes
• Consistency is key—effects are gradual and build over time
• Best results when combined with proper nutrition, exercise, and lifestyle
What are the possible side effects of Sermorelin?
Common (Typically mild):
• Redness or irritation at injection site
• Temporary flushing or warmth
• Mild headache
• Fatigue
Less Common / Rare:
• Water retention or joint stiffness
• Nausea
• Dizziness or lightheadedness